Natural killer cell toxicity
About:
This didactic animation shows the function of natural killer cells in targeting diseased cells in the body. Natural killer cells are one of the many types of white blood cells in the immune system. They have large cytoplasmic granules that contain cytotoxic proteins that can destroy pathogens and infected cells. These proteins create holes in the membrane of target cells, enabling the entry of granzymes into the cells that can cause cell death.
The goal of the animation is to help students better understand the function of natural killer cells in targeting diseased cells in the body, highlighting the involvement of cytoplasmic granules in this process. It supplements content in a self-paced eLearning module on blood cells, aiming to enhance engagement by incorporating 3D animation instead of conventional 2D graphics in the module.
Role: Storyboarding, modeling, animation, compositing
Target audience: First year medical students
Software: 3DSMax w/ Arnold, Substance Designer & Painter, Zbrush, After Effects
Format: MP4 embedded in
e-Learning module